Our bodies contain many unique physiologic systems whose sole purpose would be to maintain an internal balance called homeostasis. We know the pancreas releases insulin to balance glucose levels between the bloodstream and cells. The thyroid gland releases thyroid hormone, which regulates vital bodily functions linked to metabolism, body temperature plus much more. To put it simply, the body are working constantly to stay balanced in response to our external environment.
Inside the quest to know the way THC causes its popular intoxicating effects, scientists discovered that we have now one more regulatory physiologic system, called the endocannabinoid system (ECS), whose role is to maintain homeostasis in the messages sent between our cells. Further research shows that sickness, inflammation, and injury will trigger the ECS to take action, trying to reset our internal environment to homeostasis. This method has been referred to as being protective and essential for life. What happens if we could target this technique to stop illness and keep better health?
Endocannabinoids, sometimes called our “inner cannabis,” are synthesized when needed from healthy types of dietary fat. Cannabinoid receptors sit on the membranes of cells in particular parts of the brain and the body, namely areas inside the brain that control pain, memory, emotion, motor control, nausea, and appetite, as well as the gut, defense mechanisms, and peripheral neurological system. Should there be a trigger that triggers an imbalance, including a physical injury or illness, endocannabinoids are released, acting as “keys” that bind towards the receptors, which serve as “locks” on our cells. Once the receptor is activated, a chemical reaction takes place inside the cell, telling the cell to change its message.
ECS functioning is dependent upon many factors, including genetics, age, levels of stress, diet, and overall degree of health. There might be variants within the genes that code for the ECS which can cause propensities for certain conditions, including ADHD and PTSD. Additionally, chronic illness, chronic stress and/or chronic sleep deprivation can result in depletion of the endocannabinoids. These disruptions inside the normal functioning from the ECS hinder its ability to regulate cellular imbalances and get homeostasis.
In 2004, Ethan Russo, a neurologist and research scientist, published Clinical endocannabinoids Deficiency (CECD): Can this concept explain therapeutic benefits of cannabis in migraine, fibromyalgia, irritable bowel syndrome and other treatment-resistant conditions? in the journal Neuroendocrinology Letters. Russo theorized that particular people with the listed conditions responded to cannabis-based treatments since they had endocannabinoid deficiencies that allowed the problem to manifest in the first place.
Subsequent reports have demonstrated that endocannabinoid deficiency plays a part in autoimmune diseases, epilepsy, complex regional pain syndrome, cardiovascular disease, depression, anxiety, schizophrenia, multiple sclerosis, nausea, Huntington’s disease, Parkinson’s disease, menstrual symptoms, failure to thrive in newborns, as well as other difficult-to-treat conditions.
The cannabis plant produces over 100 phytocannabinoids, including tetrahydrocannabinol (THC) and cannabidiol (CBD). These compounds mimic the endocannabinoids by getting together with the ECS and restoring homeostasis. Rather than hold off until illness is present, there are lots of approaches to take good care of your ECS, which will allow it to function properly, avoid deficiencies and maintain homeostasis.
It’s common knowledge that a healthy, balanced eating habits are necessary for emotional and physical well-being. Your body rely on our diet to create the right amount of endocannabinoids to operate at optimal capacity. Cannabinoids are synthesized through the fatty acids in our diets and require a specific balance of omega-6 and omega-3 to become created in the correct quantities.
For max bioavailability, the ideal ratio of omega-6 to omega-3 essential fatty acids from food is between 5:1 and 1:1, the low the better for those with chronic illness. Western diets routinely consist of ratios of 20:1, mainly due to the overconsumption of omega-6 essential fatty acids which originate from vegetable oils in lots of packaged foods. Western diets with higher ratios of omega-6 to omega-3 essential fatty acids results in a lowering of endocannabinoids, resulting in the lack of ability to maintain homeostasis.
Another thing that promotes wellness from the ECS is aerobic exercise. Animal studies are convinced that voluntary wheel running increases cannabinoid receptors within the brain and boosts the sensitivity in the receptors to endocannabinoids. Human research indicates that exercise like running, biking and hiking enhance endocannabinoid levels within the bloodstream. Actually, endocannabinoids are most likely in charge of the phenomenon referred to as the “runner’s high.”
Probiotics could also benefit the ECS. Lactobacillus acidophilus, a probiotic bacteria found in fermented foods such as yogurt and sauerkraut, was demonstrated to induce the expression of cannabinoid receptors within the gut, promoting intestinal homeostasis.
Both acupuncture and osteopathic manipulation enhance the ECS. Yoga and meditation elicit the “relaxation response,” a physiological wjeflf phenomenon whereby one can consciously participate in behavior that promotes mental and physical wellness; although no research has been done to date, many experts suspect these stress management modalities improve the ECS thereby promoting homeostasis.
Lastly, have you thought about the capability of cannabis to prevent illness? Plant cannabinoids are very well-regarded as very safe and to have anti-inflammatory, antioxidant and neuroprotective properties. In cases of endocannabinoid deficiency, cannabis use may be the correcting compound, eliminating the symptoms of the disorder. Regular cannabis use can decrease chronic inflammation and buildup of free-radicals, each of which are considered to be the basis causes of many conditions, including autoimmune and neurodegenerative disorders.