Many of us are conscious of the point that slimming is a mega-dollar industry. With millions, or even vast amounts of people of every age group struggling to shed pounds, and extremely few pharmaceutically effective medications offered to assist them, the desperate public will literally clutch at straws.
Each week sees the launch of the new “miracle” slimming pill or potion along with a “surefire” diet bound to help believers shed kilos like magic.
Recently pure garcinia dr oz took over as the flavour of the year. In the event you search the net for facts about this exotic fruit extract you will be assured this is finally the miracle just about everyone has been expecting, which will produce dramatic weight reduction. Endorsements by various TV personalities as well as other luminaries have put into the allure of Garcinia cambogia slimming products.
According to a newly released local study from the Tshwane University of Technology (TUT) “this small fruit, similar to a pumpkin in appearance, is currently most popularly used and widely advertised as a weight-loss supplement”.
The comprehensive overview from TUT demonstrates that research indicates that “the extracts in addition to (-)-hydroxycitric acid (HCA), a main organic acid aspect of the fruit rind, exhibited anti-obesity activity”. Furthermore, it regulates the serotonin levels relevant to satiety, resulting in reduced diet.
“Based on clinical trial reports, Garcinia extracts were helpful to obese individuals on many occasions. Additionally, studies in the toxicity and observations during clinical studies indicate that Garcinia is safe to use. Many of the negative reports are already linked to instances when multi ingredient formulations were consumed and the effect could not be attributed to a particular ingredient.”
The research does, however, caution against a rise in serotonin, specifically in people who take medicines that are already increasing serotonin levels, for example SSRIs. Research into these effects has not been conducted.
“Moreover, regulatory authorities should provide and enforce legislation requiring the compulsory basic safety illustration showing supplements pre-marketing and develop post-marketing surveillance systems,” the research concluded.
Dr Ingrid van Heerden, a registered dietitian, is of opinion which we ought to be cautious of where can you buy garcinia cambogia extract, as it has not yet undergone rigorous testing. What follows is reviewed information from her pen, including her final verdict:
Often, once someone that wants, or needs to lose excess weight, is hooked on the promise of a slim, sexy figure, these are sucked in the deception. When the drops, wafers or powders don’t work, well then it is the fault of your user who did not abide by one or another often impossible instruction such as “stick to a 500 kcal/day diet” or “drink 5 litres of water a day”, never those of the dietary plan pill.
When eventually science and legislation catch up with the makers, they calmly take product A off the market, change their formulation slightly, affect the name to product B, after which blithely sell product B using the same advertising gambits as before, raking in the money and pulling the wool over everyone’s eyes once again.
Consistent with the ever-changing slimming product ranges, there are what you can call “ingredients of the year” (sometimes an ingredient may last for only three to six months, however, some have longer life spans, then needless to say some are resurrected every two to three years).
We have had apple cider vinegar (that has made many a comeback through the years), green tea leaf (which has earned some merit in scientific research), hoodia (which just fails to manage to make the research results that can make it a front-runner), willow bark (or salicylic acid which is useful for pains and aches although not as efficacious for slimming), and classic caffeine (that features a diuretic effect thus assisting you to shed weight before you replenish the water within your body, plus a stimulant effect when taken in big amounts that may be potentially dangerous), to mention but a few.
Even though it is perfectly likely that more extensive and well controlled scientific studies will reveal that this extract of Garcinia cambogia which contains a chemical called hydroxycitric acid (HCA) will assist weight reduction, we have been presently not even sure how this tamarind or brindall berry or brindleberry or Garcinia gummi-gutta works, what side-effects it might or might not have and what dosage is needed to achieve really significant weight-loss.
However I hear you say: “For once there exists a number of scientific research that have been conducted with Garcinia cambogia, so what’s the trouble?”
Well a few of the studies did not show any weight loss differences between patients who took Garcinia pills and people who took dummy pills, while other studies did show variations in weight loss with the subjects taking pills containing Garcinia losing slightly more weight compared to those that did not (Marquez et al, 2012).
Many of these fat loss differences were not exactly exciting either, so that we can’t say beyond doubt that Garcinia cambogia does promote weight reduction. Furthermore, it seems likely that this is not the wonder pill it can be made in the market to be.
Moreover, a lot of the studies conducted to date have already been flawed (Critchley, 2013) . What this means is designed for example that in just one study the control and experimental subjects were not well matched (i.e. they was without exactly the same starting weight, age, amount of unwanted fat etc.), during other studies too few subjects were utilized for that results to be significant.
For the outcomes of studies to become plausible one has to compare “apples with apples” (i.e. well-matched subjects and controls) and you need not only some subjects to produce a similar result.
Around the positive side, we can easily state that there exists some evidence that Garcinia cambogia products may aid weight loss over a period of 12 weeks. No reports have been conducted for much longer periods as yet (Marquez et al, 2012), which is also regarded as a drawback.
Addititionally there is currently a disagreement about the safety of pills containing Garcinia cambogia – one group of researchers slates the pills as dangerous and hepatotoxic (causing liver damage) (Kim et al, 2013), while another group refutes this (Clouatre & Preuss, 2013). Marquez and his awesome coworkers (2012) claim that “at the doses usually administered, no differences happen to be reported when it comes to side effects or adverse events (those studied) in humans between individuals addressed with G. cambogia and controls.”
Ano Lob (2009), a public health consultant in america has published a warning regarding the hepatotoxicity of a diet product called “Hydroxycut”, that contains Garcinia cambogia. The writer collected case reports of patients who developed liver toxicity linked to the previously listed weight reduction product.
Evidently approximately one million units on this hydroxycitric acid product can be bought annually in the USA. The patients who developed hepatotoxicity reported signs and symptoms of fatigue, nausea, vomiting, cramps, fever, chills, abdominal pain, and jaundice.
While the quantity of hepatotoxicity cases reported were very few, Lob points out that monitoring of adverse events linked to dietary supplements like these weight loss products is woefully inadequate in America (as is the situation in lots of other countries, including South Africa), with all the FDA only receiving about 1% of those negative reports.
As outlined by Lob (2009), the Poison Control Centres in the us are more inclined to receive reports of adverse events associated with nutritional supplements however they are not equipped to coordinate such findings.
He cites the truly sobering example of a product called “Metabolife 356″ which had been sold as a fat loss supplement in the usa. Lob’s states how the manufacturers received 14 000 reports over a duration of 5yrs that documented “serious adverse events linked to their ephedra-containing product” which dexrpky17 heart attacks, strokes, convulsions and fatalities.
The manufacturers did not inform the FDA or other US government authority of these reports. As astounding as this might sound, manufacturers of vitamin supplements usually are not necessary to meet any one of the specifications which are strictly enforced with regards to food and pharmaceutical products (medicines), so they can use this “ethical loophole” never to publish reports of negative and harmful events.
Eventually these events came to light and ephedra-containing products for slimming and also other uses were banned in the USA.
The implication contain in Lob’s warning is that HCA or Garcinia cambogia extract can also be potentially toxic unless sufficient, reliable evidence to the contrary is created available.
In the present moment, we have no idea enough about slimming goods that contain warnings of garcinia cambogia to freely recommend its use. I usually go along with Astell and coworkers (2013) who conducted a systematic report on double blind randomised controlled numerous studies to evaluate evidence available on the efficacy of current nutritional supplements utilized to control appetite and/or weight.
These authors determined that “According towards the finding with this systematic review, evidence is just not convincing in demonstrating that a majority of dietary supplements used as appetite suppressants for weight loss in the treatment of obesity are effective and safe.”
Basically we wait for more extensive and conclusive evidence obtained with larger numbers of well-matched test subjects treated for much longer periods using the “gold standard” of double blind randomised controlled clinical studies, rather stay away from any weight-loss supplement that is not tested thoroughly.